This article presents evidence that Chiropractic Spinal Adjustments (CSAs) yield positive neurophysiological outcomes related to anxiety and depression, emphasizing that the underlying mechanisms are critical. Anxiety and depression are linked to decreased alpha wave activity in the brain. Studies by Haavik, et al. (2024), demonstrated that post-CSA assessments revealed a significant increase in alpha bands, a pattern associated with reduced anxiety and improved relaxation, which persisted when retested four weeks later.

A key distinction is drawn between a CSA—a high-velocity, low-amplitude thrust directed at an identified dysfunctional vertebral motion segment—and generic spinal manipulation. Only CSAs reliably generate Central Segmental Motor Control (CSMC) changes, which are central nervous system changes affecting motor function. Research confirms that CSAs induce measurable neuroplastic changes in cortical regions (including the primary motor and somatosensory cortices), enhance maximum voluntary contractions, and increase neurological feedback (H-reflex and V-wave). Given the known risks and common long-term side effects of anxiety and depression medications, such as SSRIs and benzodiazepines, including emotional blunting and sexual dysfunction, and confirming the safety profile of chiropractic care (an extremely low adverse event rate of 0.00021%), the literature supports using chiropractic as a safe, first-line treatment for managing these mood disorders.